35th MEETING OF THE INTERNATIONAL ALDOSTERONE CONFERENCE
June 8 - 9, 2009 / Washington, DC

Oral Presentations (password is required to view files)

ALDOSTERONE AND THE KIDNEY

Caroline Ronzaud, University of Lausanne, Switzerland (contact for information: caroline.ronzaud@unil.ch)
Inducible Renal Principal Cell-specific MR Ablation in Mice

Rama Soundararajan, University of California San Francisco, USA
Molecular Players of Aldosterone Action: A Role for GILZ and the "ENaC-Regulatory-Complex" in Modulating Distal Nephron Sodium Transport

Adam Whaley-Connell, University of Missouri-Columbia School of Medicine, USA
Mineralocorticoid Receptor Antagonism Attenuates Glomerular Filtration Barrier Remodeling in the Transgenic Ren2 Rat

MR CHARACTERIZATION, EXPRESSION AND ACTIVATION

Iris Jaffe, Tufts Medical Center, USA
Aldosterone Rapidly Regulates Vascular Gene Expression via Oxidative Stress-Dependent and Independent Pathways

Roel DeRijk, University Leiden, The Netherlands
A Common Functional Human Mineralocorticoid Receptor-gene Variant Modulates Both Stress-responsiveness and Blood Pressure

Mathilde Munier, INSERM U693, France
Expression and Regulation of Mineralocorticoid Receptor during Neuronal Differentiation of Murine Embryonic Stem Cells

Jyotsna Pippal, Prince Henry's Institute of Medical Research, Australia
Characterisation of the Mineralocorticoid Receptor in Zebra Fish (Danio rerio)

Peter Fuller, Prince Henry's Institute of Medical Research, Australia
Pseudohypoaldosteronism: The Index Case Revisited

YOUNG INVESTIGATOR COMPETITION PRESENTATIONS

Celine Latouche, INSERM U872, France
In Vivo Mineralocorticoid Signaling in Cardiomyocytes: Transcriptomics from Mouse Models with Conditional and Cardiomyocyte-specific Expression of Corticosteroid Receptors

Riccardo Urbanet, Padova University, Italy
Insulin Sensitivity is not Impaired in Visceral Adipose Tissue of Patients with Primary Aldosteronism

Tim Ziera, TU Berlin, Bayer Schering Pharma AG, Germany
Identification and Functional Characterization of a Novel Primary Mineralocorticoid Receptor Target Gene

ALDOSTERONE, INSULIN AND ADIPOCYTES

Massimiliano Caprio, San Raffaele Spa, Italy
Modulation of Gene Expression in Rat Adipose Tissue in vivo Following DOC/Salt Treatment for 24h

James Luther, Vanderbilt University Medical Center, USA
Aldosterone Directly Impairs Insulin Secretion in Isolated Perifused Murine Islets

Marie Freel, University of Glasgow, The United Kingdom
Aldosterone Status Associates with Insulin Resistance in Patients with Heart Failure-data from the ALOFT Study

Patricia Underwood, Brigham and Women's Hospital, USA
The Association of Single Nucleotide Polymorphisms of the Peroxisome Proliferator-Activated Receptor Gamma (PPARg) Gene with Components of the Renin-Angiotensin-Aldosterone-System (RAAS)

MINERALOCORTICOID RECEPTOR AND THE HEART

Morag Young, Prince Henry's Institute of Medical Research, Australia
Oxidative Stress Promotes Cortisol Activation of the Mineralocorticoid Receptor in the Development of Cardiac Fibrosis

Anastasia Susie Mihailidou, Royal North Shore Hospital, Australia
Cardioprotection by Spironolactone during Experimental Myocardial Infarction: Partial Agonist and Anti-apoptotic Activity

Susana Ravassa, FIMA, Spain
Annexin A5 Mediates Cardiac Aldosterone-induced Apoptosis

Diego Alvarez de la Rosa, University of La Laguna, Spain (contact for additional information: diego.alvarez@ull.es)
The Mineralocorticoid Receptor is a Constitutive Nuclear Factor in Mouse Cardiac Myocytes

Michel Rossier, University Hospital of Geneva, Switzerland
Mineralo- and Glucocorticoid Receptors Exert their Chronotropic Action on Spontaneous Cardiomyocyte Contractions through Distinct Mechanisms

Jean-Pierre Benitah, INSERM U637, France
Aldosterone: The Missing Link of Diastolic Ca2+ Leak Induced Arrhythmias in Heart Failure?

Damien Le Menuet, INSERM U693, France
The Pacemaker Channel HCN1 is a Mineralocorticoid Receptor Target in Embryonic Stem Cell Derived Cardiomyocytes

PRIMARY ALDOSTERONISM AND HYPERTENSION

Gian Paolo Rossi, University of Padova, Italy
Impact of Accessory Hepatic Veins on Adrenal Vein Sampling for Identification of Surgically Curable Primary Aldosteronism

Sheerazed Boulkroun, INSERM U970, France
Transcriptional Analysis and Functional Anatomy of Primary Aldosteronism

Bernhard Schmidt, Hannover Medical School, Germany
Vascular Target Organ Damage is Improved by Low Dose Eplerenone

Samantha Alvarez-Madrazo, University of Glasgow, United Kingdom
Association of Narrower Regions in CYP11B1/B2 Locus with Hypertension in Caucasians

REGULATION OF ALDOSTERONE PRODUCTION

Scott MacKenzie, University of Glasgow, United Kingdom
Common Genetic Polymorphisms Result in Altered 11B-Hydroxylase and Aldosterone Synthase Transcription in Human Adrenal Cortex

Akira Uruno, Tohoku University Graduate School of Medicine, Japan
PPARgamma Suppresses Angiotensin II- and Potassium-induced CYP11B2 Expression and Aldosterone Production in Adrenocortical Carcinoma H295 Cells

Wendy Bollag, Medical College of Georgia, USA
Protein Kinase C and Src Kinase Mediate Angiotension II-Induced Activation of Protein Kinase D in and Aldosterone Secretion from Bovine Adrenal Glomerulosa Cells

Yewei Xing, Medical College of Georgia, USA
High Density Lipoprotein Increases Aldosterone Production in Human Adrenocorticoid Cells by Stimulating Expression of Aldosterone Synthase (CYP11B2)

Stacy Wood, University of Glasgow, United Kingdom
MicroRNA: A Novel Post-transcriptional Regulator of 11B-Hydroxylase (CYP11B1) and Aldosterone Synthase (CYP11B2)